Publications

The Cancer Therapy Evaluation Program (CTEP) has developed an enterprise system designed to enhance the scientific and administrative aspects of cancer clinical trial development. Faced with a maturing enterprise system, CTEP is migrating to a Service Oriented Architecture (SOA), which will reduce long-term maintenance cost without sacrificing flexibility, and will enhance the continuous improvement of the clinical trial development process by converging with the cancer Biomedical Informatics Grid (caBIG™). This paper outlines the reengineering process CTEP is using to move towards an SOA for its enterprise system.
Download »

The TrialBridge™ framework is a unique proprietary software solution or technology stack designed by CTIS based on our wide experience in the CTRM space. This paper concentrates on the interoperable framework that helps sponsors tailor, standardize, control, and improve the quality of clinical data, which in turn allows us to bring products to market more quickly with the highest level of quality.
Download »

The Performance Pyramid illustrates that through proper use of IT, process reengineering, and organization optimization, the gaps, duplication, and fragmentation currently found in the overall health industry can be transformed into an end-to-end care solution for the whole population, while reducing cost.
Download »

Translational Research has proven to be a powerful process that drives the clinical research engine. This paper highlights the gaps in existing informatics platforms supporting the therapeutic drug discovery and development life cycle. It also addresses the different points of view for researchers, oncologists, and patients, which would help individualize therapy.
Download »

As society continues to race into the Knowledge Age, CTIS has built consulting practices around its information, technology, applications, software solutions, and products that serve the purpose of moving our society in that direction. This paper focuses on how knowledge worker and informatics systems dramatically improve return on investment during the Knowledge Age.
Download »

CTIS has built powerful clinical trial and research management (CTRM) informatics applications that help in improving and accelerating the clinical trial process. This paper highlights our commitment to build CTRM informatics to improve the support for clinical research with highest performance, earned vValue management, and return on investment.
Download »

EnSURe™ provides our clients with the necessary training tools and processes that enable a standard and efficient method of delivering IT services and solutions to our respective clients so they can make the right IT investment choices.
Download »

In order to realize the full value of health IT, a robust economic framework must be developed that allows for innovations to take hold. This proposed model couples ecology with basic economics for an approach that incentivizes participation by the entire health ecosystem.
Download »

The mEMR application developed by CTIS is designed with physicians and health professionals in mind. It is a digital dashboard enabling efficient clinical workflows and informed care decisions.
Download »

The mWarrior application developed by CTIS is designed with our active military and veterans in mind. It is a survey-based solution designed to improve early detection, screening, and treatment for Post-traumatic stress disorder (PTSD).
Download »

HIE is a necessary building block upon which the digital health community can meaningfully harness the power of Health Information Technology (HIT) to facilitate the future of healthcare in your community. Our five-layer IT solution enables stakeholders to seamlessly deliver health information across a wide range of information sources and users.
Download »

A Digital Health Community should have the capability of exchanging necessary information on- demand and across the healthcare spectrum. Our four-layer IT solution focuses on prevention, to managing an acute attack, to post-attack management, to secondary prevention in order to better serve the patient’s needs.
Download »

Safety Profiler facilitates the clinical data assessment, grading, and reporting of adverse events during the clinical trial process, making it easier to accurately record adverse events at the point of care.
Download »

The health disparity population requires interventions to bridge the gap in quality care resulting from resource limitations such as inadequate physician access and financial burdens. We are committed to being a part of the solution and we have displayed our commitment through our community involvement and have developed solutions to directly address these issues.
Download »

CTIS has engaged in many Global Health projects resulting in measurable outcomes and significant impact worldwide in over 30 countries, including Africa, Europe, India, Latin America, and Middle East. We have applied our proven health informatics, innovative, and highly collaborative services in many diverse settings.
Download »

eRIC is designed to automate the submission, tracking, and review of scientific regulatory and compliance information that is required for the safe conduct of human subjects research. It benefits stakeholder committees, such as the Institutional Review Board (IRB) and the Cancer Research Committee (CRC); clinical researchers; regulatory bodies; and improves overall public trust in pre-clinical and clinical research processes.
Download »

Docu-MART was developed to assist the authoring, reviewing, and tracking of clinical trial protocol documents. This system facilitates expedited processing, resulting in faster research and development and the earlier discovery of new drug treatments, thereby enhancing patient care.
Download »

This brochure defines the CTRM stakeholders and our four-layer solution stack that address the clinical research lifecycle needs. Our solution facilitates collaboration, increases efficacy, and shortens the bench-to-beside timeframes and costs. It increases process efficiency and productivity among the stakeholders and their ability to access the right information at the right time.
Download »

The CTIS-developed mPHR 2 application is designed to overcome the many bottlenecks and redundancies existing in today’s healthcare system that limit real-time access to individual patient health information. This brochure showcases the features, capabilities, and nine health modules of this one-stop shop for your personalized health records.
Download »

What can health informatics offer you? This brochure discusses how our IT solutions address the most pressing issues in the health system today for patients, health professionals, health systems, research organizations, and payors.
Download »

This brochure highlights CTIS’ experience in implementing informatics solutions in key areas of the Global Health Initiative. CTIS has engaged in many Global Health projects that resulted in measurable outcomes and significant impact worldwide in over 30 countries, including Africa, Europe, India, Latin America, and the Middle East.
Download »

CTIS offers a wide range of MHS comprised of proven industry-tested solutions that enable clients to consolidate and modernize their existing infrastructure and service offerings, while reducing their total cost of operations. Tailored solutions offer industry standard security, compliance, and best practices.
Download »

CTIS’ value proposition is to deliver the highest return on investment and value to our clients. We ensure our clients achieve clear, tangible results through the use of our innovative products and services by combining the right team and the right approach that deliver the right results.
Download »

Our SD services offer ‘end-to-end’ services to develop applications and architecture. This brochure showcases our process approach and our software development methodology that facilitates collaboration amongst the institute participants, ensures the quality of information, and improves professional productivity, process streamlining, and organizational effectiveness.
Download »

CTIS offers integrated PM services through CTIS’ trained and certified Project Management Professionals who focus on quality service and customer satisfaction. This brochure provides details on the processes and activities involved in our Integrated Program Management Approach -- IT Strategy, IT Delivery, and IT Evaluation.
Download »

Good Clinical Practice (GCP) is an international ethical and scientific quality standard for designing, conducting, recording, and reporting trials that involve the participation of human subjects. Our proprietary framework addresses the ethical and safety obligations inherent in the use of informatics. Our approach and tools are collectively referred to as Good Clinical Informatics™ (GCI).
Download »

This brochure highlights our 25 years proven history in providing total informatics solutions to the health sector by building innovative, appropriate, timely, and best quality information technology solutions.
Download »

This vision for transformation of the health system focuses on performance and innovation-driven, quality healthcare that provides the best patient safety and care outcomes. The results are increased operating efficiency, effectiveness and productivity; reduced cost; highest return on investment; ACO compliance; evidence-based medicine; and sustainability.
Download »

Highlights the clinical trial process lifecycle, its rate limiting factors, and our CTRM solution stack. Overview of the products developed during each phase of the lifecycle: Trial Planning, Activation, Conduct and Reporting.
Download »

IT-driven value management components at the patient and enterprise levels. Generating better care and population health for patients and cost reduction and increased funding for enterprises.
Download »

CTIS developed a solution for the Division of Intramural Research (DIR) and the Office of Biostatistics Research (OBR) at NHLBI that reduces the actual development time for new case report forms and medical record reports by 15%.
Download »

IPAD lets sponsors, regulators, and principal investigators obtain information about agents and compounds instantly and accurately, placing them in a better position to make informed decisions.
Download »

CTIS developed a survey management system for DCEG to investigate the relationship between diet and cancer in three locations in India. It is built on a dynamic form engine component and facilitates easy development of multi-lingual case report forms.
Download »

Safety Profiler leverages wireless information technology to facilitate the clinical data assessment, grading, and reporting of adverse events during the clinical trial process, making it easier to accurately record adverse events at the point of care.
Download »

CTIS developed an enterprise solution for National Institute of Allergy and Infectious Diseases (NIAID). DAIDS-ES strengthens safety and pharmacovigilance monitoring; improves data quality, integrity and stability; and allows for rapid, secure, and accurate adverse event reporting globally.
Download »

CTIS developed a worldwide clinical trial and data management system with a web-based portal that is currently used by four participating centers in the treatment of the Acute Lymphoblastic Leukemia (ALL) study group in India. It has accrued about 450 patients so far.
Download »

CTIS has successfully implemented and integrated over 25 software components through our managed hosting environment for North Carolina Healthcare Information and Communications Alliance (NCHICA) and MedVA.
Download »

OERC provides open-source learning modules in the area of cancer research and training worldwide that will be available for free to all physicians, nursing, teaching staff, and patients. This enhances the capacity of health policy makers, medical institutions, hospitals, and clinics to access knowledge and research cancer-related results.
Download »

Docu-MART facilitates collaborative protocol development; improves document tracking; and streamlines protocol submissions. Docu-MART has decreased the processing time (Letter of Intent to Activation) from 550 days to 200 days and increased the number of protocols by 283%.
Download »

eRIC delivers a diversified and convenient solution for research administrative tasks. It promotes real-time interaction between regulatory agencies and research communities and improves overall public trust in pre-clinical and clinical research processes.
Download »

CTIS developed an enterprise solution for National Cancer Institute's (NCI), CTEP-ESYS, that was rated number two out of six major NIH investments and delivers an average return on investment of over 250%.
Download »

Aurora supports electronic submission of clinical trial investigator information to trial sponsors and regulatory bodies. It automates the existing FDA 1572 registration process, allowing investigators to centrally maintain and manage all FDA 1572 registrations.
Download »